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How eggs arrest at metaphase II: MPF stabilisation plus APC/C inhibition equals Cytostatic Factor

Oocytes from higher chordates, including man and nearly all mammals, arrest at metaphase of the second meiotic division before fertilization. This arrest is due to an activity that has been termed 'Cytostatic Factor'. Cytostatic Factor maintains arrest through preventing loss in Maturation...

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Detalles Bibliográficos
Autores principales: Madgwick, Suzanne, Jones, Keith T
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1794241/
https://www.ncbi.nlm.nih.gov/pubmed/17257429
http://dx.doi.org/10.1186/1747-1028-2-4