Overestimating resistance in field testing of malaria parasites: simple methods for estimating high EC(50 )values using a Bayesian approach

Conventional methods of assessing in-vitro antimalarial drug-concentration effect relationships in field testing of fresh isolates assess each parasite isolate individually. This leads to systematic overestimation of EC(50 )values for the most resistant isolates, and thus overestimation of the degre...

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Detalles Bibliográficos
Autores principales: Stepniewska, Kasia, Chotivanich, Kesinee, Brockman, Alan, Day, Nicholas PJ, White, Nicholas J
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1794247/
https://www.ncbi.nlm.nih.gov/pubmed/17229314
http://dx.doi.org/10.1186/1475-2875-6-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1794247/
https://www.ncbi.nlm.nih.gov/pubmed/17229314
http://dx.doi.org/10.1186/1475-2875-6-4

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