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Overestimating resistance in field testing of malaria parasites: simple methods for estimating high EC(50 )values using a Bayesian approach
Conventional methods of assessing in-vitro antimalarial drug-concentration effect relationships in field testing of fresh isolates assess each parasite isolate individually. This leads to systematic overestimation of EC(50 )values for the most resistant isolates, and thus overestimation of the degre...
Autores principales: | Stepniewska, Kasia, Chotivanich, Kesinee, Brockman, Alan, Day, Nicholas PJ, White, Nicholas J |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2007
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1794247/ https://www.ncbi.nlm.nih.gov/pubmed/17229314 http://dx.doi.org/10.1186/1475-2875-6-4 |
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