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Toll-like receptor activation enhances cell-mediated immunity induced by an antibody vaccine targeting human dendritic cells

Previously, we have successfully targeted the mannose receptor (MR) expressed on monocyte-derived dendritic cells (DCs) using a fully human MR-specific antibody, B11, as a vehicle to deliver whole protein tumor antigens such as the human chorionic gonadotropin hormone (hCGβ). Since MRs play a role i...

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Detalles Bibliográficos
Autores principales: Ramakrishna, Venky, Vasilakos, John P, Tario, Joseph D, Berger, Marc A, Wallace, Paul K, Keler, Tibor
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1794405/
https://www.ncbi.nlm.nih.gov/pubmed/17254349
http://dx.doi.org/10.1186/1479-5876-5-5