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Toll-like receptor activation enhances cell-mediated immunity induced by an antibody vaccine targeting human dendritic cells
Previously, we have successfully targeted the mannose receptor (MR) expressed on monocyte-derived dendritic cells (DCs) using a fully human MR-specific antibody, B11, as a vehicle to deliver whole protein tumor antigens such as the human chorionic gonadotropin hormone (hCGβ). Since MRs play a role i...
Autores principales: | Ramakrishna, Venky, Vasilakos, John P, Tario, Joseph D, Berger, Marc A, Wallace, Paul K, Keler, Tibor |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2007
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1794405/ https://www.ncbi.nlm.nih.gov/pubmed/17254349 http://dx.doi.org/10.1186/1479-5876-5-5 |
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