The sensitivity of murine spermiogenesis to miglustat is a quantitative trait: a pharmacogenetic study

BACKGROUND: A major event in the post-meiotic development of male germ cells is the formation of the acrosome. This process can be perturbed in C57BL/6 mice by administration of the small molecule miglustat (N-butyldeoxynojirimycin, NB-DNJ). The miglustat-treated mice produce morphologically abnorma...

Descripción completa

Detalles Bibliográficos
Autores principales: Bone, Wilhelm, Walden, Charlotte M, Fritsch, Martin, Voigtmann, Ulrike, Leifke, Eckhard, Gottwald, Ulrich, Boomkamp, Stephanie, Platt, Frances M, van der Spoel, Aarnoud C
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1794412/
https://www.ncbi.nlm.nih.gov/pubmed/17241468
http://dx.doi.org/10.1186/1477-7827-5-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1794412/
https://www.ncbi.nlm.nih.gov/pubmed/17241468
http://dx.doi.org/10.1186/1477-7827-5-1

Ejemplares similares