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The sensitivity of murine spermiogenesis to miglustat is a quantitative trait: a pharmacogenetic study
BACKGROUND: A major event in the post-meiotic development of male germ cells is the formation of the acrosome. This process can be perturbed in C57BL/6 mice by administration of the small molecule miglustat (N-butyldeoxynojirimycin, NB-DNJ). The miglustat-treated mice produce morphologically abnorma...
| Autores principales: | , , , , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2007
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1794412/ https://www.ncbi.nlm.nih.gov/pubmed/17241468 http://dx.doi.org/10.1186/1477-7827-5-1 |