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Bench-to-bedside review: The role of activated protein C in maintaining endothelial tight junction function and its relationship to organ injury
Activated protein C (APC) has emerged as a novel therapeutic agent for use in selected patients with severe sepsis, even though the mechanism of its benefit is not well established. APC has anticoagulant, anti-inflammatory, antiapoptotic, and profibrinolytic properties, but it is not clear through w...
| Autores principales: | , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2006
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1794467/ https://www.ncbi.nlm.nih.gov/pubmed/17169139 http://dx.doi.org/10.1186/cc5099 |