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Hepatocyte growth factor ameliorates dermal sclerosis in the tight-skin mouse model of scleroderma

The tight-skin (TSK/+) mouse, a genetic model of systemic sclerosis (SSc), develops cutaneous fibrosis and defects in pulmonary architecture. Because hepatocyte growth factor (HGF) is an important mitogen and morphogen that contributes to the repair process after tissue injury, we investigated the r...

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Detalles Bibliográficos
Autores principales: Iwasaki, Tsuyoshi, Imado, Takehito, Kitano, Sachie, Sano, Hajime
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1794503/
https://www.ncbi.nlm.nih.gov/pubmed/17049072
http://dx.doi.org/10.1186/ar2068