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P5L mutation in Ank results in an increase in extracellular inorganic pyrophosphate during proliferation and nonmineralizing hypertrophy in stably transduced ATDC5 cells

Ank is a multipass transmembrane protein that regulates the cellular transport of inorganic pyrophosphate. In the progressive ankylosis (ank) mouse, a premature termination mutation at glutamic acid 440 results in a phenotype characterized by inappropriate deposition of basic calcium phosphate cryst...

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Detalles Bibliográficos
Autores principales: Zaka, Raihana, Stokes, David, Dion, Arnold S, Kusnierz, Anna, Han, Fei, Williams, Charlene J
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1794507/
https://www.ncbi.nlm.nih.gov/pubmed/17067391
http://dx.doi.org/10.1186/ar2072