Transition of healthy to diseased synovial tissue in rheumatoid arthritis is associated with gain of mesenchymal/fibrotic characteristics

The healthy synovial lining layer consists of a single cell layer that regulates the transport between the joint cavity and the surrounding tissue. It has been suggested that abnormalities such as somatic mutations in the p53 tumor-suppressor gene contribute to synovial hyperplasia and invasion in r...

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Detalles Bibliográficos
Autores principales: Steenvoorden, Marjan MC, Tolboom, Tanja CA, van der Pluijm, Gabri, Löwik, Clemens, Visser, Cornelis PJ, DeGroot, Jeroen, Gittenberger-DeGroot, Adriana C, DeRuiter, Marco C, Wisse, Bert J, Huizinga, Tom WJ, Toes, René EM
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1794508/
https://www.ncbi.nlm.nih.gov/pubmed/17076892
http://dx.doi.org/10.1186/ar2073

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1794508/
https://www.ncbi.nlm.nih.gov/pubmed/17076892
http://dx.doi.org/10.1186/ar2073

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