Abnormal insulin-like growth factor 1 signaling in human osteoarthritic subchondral bone osteoblasts

Insulin-like growth factor (IGF)-1 is a key factor in bone homeostasis and could be involved in bone tissue sclerosis as observed in osteoarthritis (OA). Here, we compare the key signaling pathways triggered in response to IGF-1 stimulation between normal and OA osteoblasts (Obs). Primary Obs were p...

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Detalles Bibliográficos
Autores principales: Massicotte, Frédéric, Aubry, Isabelle, Martel-Pelletier, Johanne, Pelletier, Jean-Pierre, Fernandes, Julio, Lajeunesse, Daniel
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1794522/
https://www.ncbi.nlm.nih.gov/pubmed/17129375
http://dx.doi.org/10.1186/ar2087

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1794522/
https://www.ncbi.nlm.nih.gov/pubmed/17129375
http://dx.doi.org/10.1186/ar2087

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