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Abnormal insulin-like growth factor 1 signaling in human osteoarthritic subchondral bone osteoblasts
Insulin-like growth factor (IGF)-1 is a key factor in bone homeostasis and could be involved in bone tissue sclerosis as observed in osteoarthritis (OA). Here, we compare the key signaling pathways triggered in response to IGF-1 stimulation between normal and OA osteoblasts (Obs). Primary Obs were p...
| Autores principales: | , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2006
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1794522/ https://www.ncbi.nlm.nih.gov/pubmed/17129375 http://dx.doi.org/10.1186/ar2087 |