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The shunt from the cyclooxygenase to lipoxygenase pathway in human osteoarthritic subchondral osteoblasts is linked with a variable expression of the 5-lipoxygenase-activating protein

Osteoarthritis (OA) is characterized by articular cartilage degradation and hypertrophic bone changes with osteophyte formation and abnormal bone remodeling. Two groups of OA patients were identified via the production of variable and opposite levels of prostaglandin E(2 )(PGE(2)) or leukotriene B(4...

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Detalles Bibliográficos
Autores principales: Maxis, Kelitha, Delalandre, Aline, Martel-Pelletier, Johanne, Pelletier, Jean-Pierre, Duval, Nicolas, Lajeunesse, Daniel
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1794527/
https://www.ncbi.nlm.nih.gov/pubmed/17156456
http://dx.doi.org/10.1186/ar2092