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The role of synovial macrophages and macrophage-produced cytokines in driving aggrecanases, matrix metalloproteinases, and other destructive and inflammatory responses in osteoarthritis

There is an increasing body of evidence that synovitis plays a role in the progression of osteoarthritis and that overproduction of cytokines and growth factors from the inflamed synovium can influence the production of degradative enzymes and the destruction of cartilage. In this study, we investig...

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Detalles Bibliográficos
Autores principales: Bondeson, Jan, Wainwright, Shane D, Lauder, Sarah, Amos, Nick, Hughes, Clare E
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1794533/
https://www.ncbi.nlm.nih.gov/pubmed/17177994
http://dx.doi.org/10.1186/ar2099