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The role of synovial macrophages and macrophage-produced cytokines in driving aggrecanases, matrix metalloproteinases, and other destructive and inflammatory responses in osteoarthritis
There is an increasing body of evidence that synovitis plays a role in the progression of osteoarthritis and that overproduction of cytokines and growth factors from the inflamed synovium can influence the production of degradative enzymes and the destruction of cartilage. In this study, we investig...
Autores principales: | Bondeson, Jan, Wainwright, Shane D, Lauder, Sarah, Amos, Nick, Hughes, Clare E |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2006
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1794533/ https://www.ncbi.nlm.nih.gov/pubmed/17177994 http://dx.doi.org/10.1186/ar2099 |
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