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Retroviral activation of the mir-106a microRNA cistron in T lymphoma

Retroviral insertion into a host genome is a powerful tool not only for the discovery of cancer genes, but also for the discovery of potential oncogenic noncoding RNAs. In a large-scale mouse T lymphocyte tumor screen we found a high density of integrations upstream of the mir-106a microRNA cistron....

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Detalles Bibliográficos
Autores principales: Lum, Amy M, Wang, Bruce B, Li, Lauri, Channa, Namitha, Bartha, Gabor, Wabl, Matthias
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1794537/
https://www.ncbi.nlm.nih.gov/pubmed/17442096
http://dx.doi.org/10.1186/1742-4690-4-5