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Predicting domain-domain interactions using a parsimony approach

We propose a novel approach to predict domain-domain interactions from a protein-protein interaction network. In our method we apply a parsimony-driven explanation of the network, where the domain interactions are inferred using linear programming optimization, and false positives in the protein net...

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Detalles Bibliográficos
Autores principales: Guimarães, Katia S, Jothi, Raja, Zotenko, Elena, Przytycka, Teresa M
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1794579/
https://www.ncbi.nlm.nih.gov/pubmed/17094802
http://dx.doi.org/10.1186/gb-2006-7-11-r104