How complete are current yeast and human protein-interaction networks?

We estimate the full yeast protein-protein interaction network to contain 37,800-75,500 interactions and the human network 154,000-369,000, but owing to a high false-positive rate, current maps are roughly only 50% and 10% complete, respectively. Paradoxically, releasing raw, unfiltered assay data m...

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Detalles Bibliográficos
Autores principales: Hart, G Traver, Ramani, Arun K, Marcotte, Edward M
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Opinion
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1794583/
https://www.ncbi.nlm.nih.gov/pubmed/17147767
http://dx.doi.org/10.1186/gb-2006-7-11-120

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1794583/
https://www.ncbi.nlm.nih.gov/pubmed/17147767
http://dx.doi.org/10.1186/gb-2006-7-11-120

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