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FlowerPower: clustering proteins into domain architecture classes for phylogenomic inference of protein function

BACKGROUND: Function prediction by transfer of annotation from the top database hit in a homology search has been shown to be prone to systematic error. Phylogenomic analysis reduces these errors by inferring protein function within the evolutionary context of the entire family. However, accuracy of...

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Detalles Bibliográficos
Autores principales: Krishnamurthy, Nandini, Brown, Duncan, Sjölander, Kimmen
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1796606/
https://www.ncbi.nlm.nih.gov/pubmed/17288570
http://dx.doi.org/10.1186/1471-2148-7-S1-S12