Effect of chloroquine on reducing HIV-1 replication in vitro and the DC-SIGN mediated transfer of virus to CD4(+ )T-lymphocytes

BACKGROUND: Chloroquine (CQ) has been shown to inhibit HIV-1 replication in vitro as well as in vivo and has been proposed to alter the glycosylation pattern of the gp120 envelope. These activities indicate that the compound can be used not only as an effective HIV-1 therapeutic agent but also as a...

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Detalles Bibliográficos
Autores principales: Naarding, Marloes A, Baan, Elly, Pollakis, Georgios, Paxton, William A
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1796897/
https://www.ncbi.nlm.nih.gov/pubmed/17263871
http://dx.doi.org/10.1186/1742-4690-4-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1796897/
https://www.ncbi.nlm.nih.gov/pubmed/17263871
http://dx.doi.org/10.1186/1742-4690-4-6

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