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Depletion of ceramides with very long chain fatty acids causes defective skin permeability barrier function, and neonatal lethality in ELOVL4 deficient mice

Very long chain fatty acids (VLCFA), either free or as components of glycerolipids and sphingolipids, are present in many organs. Elongation of very long chain fatty acids-4 (ELOVL4) belongs to a family of 6 members of putative fatty acid elongases that are involved in the formation of VLCFA. Mutati...

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Detalles Bibliográficos
Autores principales: Li, Wenmei, Sandhoff, Roger, Kono, Mari, Zerfas, Patricia, Hoffmann, Vickie, Ding, Bryan Char-Hoa, Proia, Richard L., Deng, Chu-Xia
Formato: Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1796950/
https://www.ncbi.nlm.nih.gov/pubmed/17311087