RNAi-based conditional gene knockdown in mice using a U6 promoter driven vector

RNA interference (RNAi) is a powerful tool widely used for studying gene function in a number of species. We have previously developed an approach that allows conditional expression of a polymerase III promoter based small hairpin RNA (shRNA) in mice using the Cre-LoxP system. This approach uses a U...

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Detalles Bibliográficos
Autores principales: Shukla, Vivek, Coumoul, Xavier, Deng, Chu-Xia
Formato: Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2007
Materias:
Technical Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1796951/
https://www.ncbi.nlm.nih.gov/pubmed/17304337

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1796951/
https://www.ncbi.nlm.nih.gov/pubmed/17304337

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