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RNAi-based conditional gene knockdown in mice using a U6 promoter driven vector
RNA interference (RNAi) is a powerful tool widely used for studying gene function in a number of species. We have previously developed an approach that allows conditional expression of a polymerase III promoter based small hairpin RNA (shRNA) in mice using the Cre-LoxP system. This approach uses a U...
Autores principales: | Shukla, Vivek, Coumoul, Xavier, Deng, Chu-Xia |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Ivyspring International Publisher
2007
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1796951/ https://www.ncbi.nlm.nih.gov/pubmed/17304337 |
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