Cargando…

Production of recombinant antibody fragments in Bacillus megaterium

BACKGROUND: Recombinant antibodies are essential reagents for research, diagnostics and therapy. The well established production host Escherichia coli relies on the secretion into the periplasmic space for antibody synthesis. Due to the outer membrane of Gram-negative bacteria, only a fraction of th...

Descripción completa

Detalles Bibliográficos
Autores principales: Jordan, Eva, Hust, Michael, Roth, Andreas, Biedendieck, Rebekka, Schirrmann, Thomas, Jahn, Dieter, Dübel, Stefan
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1797049/
https://www.ncbi.nlm.nih.gov/pubmed/17224052
http://dx.doi.org/10.1186/1475-2859-6-2