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Production of recombinant antibody fragments in Bacillus megaterium
BACKGROUND: Recombinant antibodies are essential reagents for research, diagnostics and therapy. The well established production host Escherichia coli relies on the secretion into the periplasmic space for antibody synthesis. Due to the outer membrane of Gram-negative bacteria, only a fraction of th...
Autores principales: | Jordan, Eva, Hust, Michael, Roth, Andreas, Biedendieck, Rebekka, Schirrmann, Thomas, Jahn, Dieter, Dübel, Stefan |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2007
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1797049/ https://www.ncbi.nlm.nih.gov/pubmed/17224052 http://dx.doi.org/10.1186/1475-2859-6-2 |
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