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Reduction of gene repair by selenomethionine with the use of single-stranded oligonucleotides

BACKGROUND: The repair of single base mutations in mammalian genes can be directed by single-stranded oligonucleotides in a process known as targeted gene repair. The mechanism of this reaction is currently being elucidated but likely involves a pairing step in which the oligonucleotide align in hom...

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Detalles Bibliográficos
Autores principales: Schwartz, Timothy R, Kmiec, Eric B
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1797052/
https://www.ncbi.nlm.nih.gov/pubmed/17257432
http://dx.doi.org/10.1186/1471-2199-8-7