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Reduction of gene repair by selenomethionine with the use of single-stranded oligonucleotides
BACKGROUND: The repair of single base mutations in mammalian genes can be directed by single-stranded oligonucleotides in a process known as targeted gene repair. The mechanism of this reaction is currently being elucidated but likely involves a pairing step in which the oligonucleotide align in hom...
| Autores principales: | , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2007
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1797052/ https://www.ncbi.nlm.nih.gov/pubmed/17257432 http://dx.doi.org/10.1186/1471-2199-8-7 |