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Factor interaction analysis for chromosome 8 and DNA methylation alterations highlights innate immune response suppression and cytoskeletal changes in prostate cancer

BACKGROUND: Alterations of chromosome 8 and hypomethylation of LINE-1 retrotransposons are common alterations in advanced prostate carcinoma. In a former study including many metastatic cases, they strongly correlated with each other. To elucidate a possible interaction between the two alterations,...

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Detalles Bibliográficos
Autores principales: Schulz, Wolfgang A, Alexa, Adrian, Jung, Volker, Hader, Christiane, Hoffmann, Michèle J, Yamanaka, Masanori, Fritzsche, Sandy, Wlazlinski, Agnes, Müller, Mirko, Lengauer, Thomas, Engers, Rainer, Florl, Andrea R, Wullich, Bernd, Rahnenführer, Jörg
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1797054/
https://www.ncbi.nlm.nih.gov/pubmed/17280610
http://dx.doi.org/10.1186/1476-4598-6-14