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Association of warfarin dose with genes involved in its action and metabolism

We report an extensive study of variability in genes encoding proteins that are believed to be involved in the action and biotransformation of warfarin. Warfarin is a commonly prescribed anticoagulant that is difficult to use because of the wide interindividual variation in dose requirements, the na...

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Detalles Bibliográficos
Autores principales: Wadelius, Mia, Chen, Leslie Y., Eriksson, Niclas, Bumpstead, Suzannah, Ghori, Jilur, Wadelius, Claes, Bentley, David, McGinnis, Ralph, Deloukas, Panos
Formato: Texto
Lenguaje:English
Publicado: Springer-Verlag 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1797064/
https://www.ncbi.nlm.nih.gov/pubmed/17048007
http://dx.doi.org/10.1007/s00439-006-0260-8