Resistance of the target islet tissue to autoimmune destruction contributes to genetic susceptibility in Type 1 diabetes

Type 1 diabetes occurs when self-reactive T lymphocytes destroy the insulin-producing islet β cells of the pancreas. The defects causing this disease have often been assumed to occur exclusively in the immune system. We present evidence that genetic variation at the Idd9 diabetes susceptibility locu...

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Detalles Bibliográficos
Autores principales: Hill, Natasha J, Stotland, Aleksandr, Solomon, Michelle, Secrest, Patrick, Getzoff, Elizabeth, Sarvetnick, Nora
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1797159/
https://www.ncbi.nlm.nih.gov/pubmed/17254331
http://dx.doi.org/10.1186/1745-6150-2-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1797159/
https://www.ncbi.nlm.nih.gov/pubmed/17254331
http://dx.doi.org/10.1186/1745-6150-2-5

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