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Ovarian dysgerminomas are characterised by frequent KIT mutations and abundant expression of pluripotency markers

BACKGROUND: Ovarian germ cell tumours (OGCTs) typically arise in young females and their pathogenesis remains poorly understood. We investigated the origin of malignant OGCTs and underlying molecular events in the development of the various histological subtypes of this neoplasia. RESULTS: We examin...

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Detalles Bibliográficos
Autores principales: Hoei-Hansen, Christina E, Kraggerud, Sigrid M, Abeler, Vera M, Kærn, Janne, Rajpert-De Meyts, Ewa, Lothe, Ragnhild A
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1797189/
https://www.ncbi.nlm.nih.gov/pubmed/17274819
http://dx.doi.org/10.1186/1476-4598-6-12