Src Homology 2–containing 5-Inositol Phosphatase (SHIP) Suppresses an Early Stage of Lymphoid Cell Development through Elevated Interleukin-6 Production by Myeloid Cells in Bone Marrow

The Src homology (SH)2–containing inositol 5-phosphatase (SHIP) negatively regulates a variety of immune responses through inhibitory immune receptors. In SHIP(−/−) animals, we found that the number of early lymphoid progenitors in the bone marrow was significantly reduced and accompanied by expansi...

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Detalles Bibliográficos
Autores principales: Nakamura, Koji, Kouro, Taku, Kincade, Paul W., Malykhin, Alexander, Maeda, Kazuhiko, Coggeshall, K. Mark
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2004
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1797415/
https://www.ncbi.nlm.nih.gov/pubmed/14718513
http://dx.doi.org/10.1084/jem.20031193

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1797415/
https://www.ncbi.nlm.nih.gov/pubmed/14718513
http://dx.doi.org/10.1084/jem.20031193

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