Epigenetic Activation of a Subset of mRNAs by eIF4E Explains Its Effects on Cell Proliferation

BACKGROUND: Translation deregulation is an important mechanism that causes aberrant cell growth, proliferation and survival. eIF4E, the mRNA 5′ cap-binding protein, plays a major role in translational control. To understand how eIF4E affects cell proliferation and survival, we studied mRNA targets t...

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Detalles Bibliográficos
Autores principales: Mamane, Yaël, Petroulakis, Emmanuel, Martineau, Yvan, Sato, Taka-Aki, Larsson, Ola, Rajasekhar, Vinagolu K., Sonenberg, Nahum
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2007
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1797416/
https://www.ncbi.nlm.nih.gov/pubmed/17311107
http://dx.doi.org/10.1371/journal.pone.0000242

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1797416/
https://www.ncbi.nlm.nih.gov/pubmed/17311107
http://dx.doi.org/10.1371/journal.pone.0000242

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