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Epigenetic Activation of a Subset of mRNAs by eIF4E Explains Its Effects on Cell Proliferation
BACKGROUND: Translation deregulation is an important mechanism that causes aberrant cell growth, proliferation and survival. eIF4E, the mRNA 5′ cap-binding protein, plays a major role in translational control. To understand how eIF4E affects cell proliferation and survival, we studied mRNA targets t...
| Autores principales: | , , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2007
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1797416/ https://www.ncbi.nlm.nih.gov/pubmed/17311107 http://dx.doi.org/10.1371/journal.pone.0000242 |