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Reduced influenza viral neutralizing activity of natural human trimers of surfactant protein D

BACKGROUND: Surfactant protein D (SP-D) plays important roles in innate host defense against influenza A virus (IAV) infection. Common human polymorphisms of SP-D have been found in many human populations and associated with increased risk of certain infections. We recently reported that the Thr/Thr...

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Detalles Bibliográficos
Autores principales: Hartshorn, Kevan L, White, Mitchell R, Tecle, Tesfaldet, Tornoe, Ida, Sorensen, Grith L, Crouch, Erika C, Holmskov, Uffe
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1797806/
https://www.ncbi.nlm.nih.gov/pubmed/17280604
http://dx.doi.org/10.1186/1465-9921-8-9