An Unmethylated 3′ Promoter-Proximal Region Is Required for Efficient Transcription Initiation

The promoter regions of approximately 40% of genes in the human genome are embedded in CpG islands, CpG-rich regions that frequently extend on the order of one kb 3′ of the transcription start site (TSS) region. CpGs 3′ of the TSS of actively transcribed CpG island promoters typically remain methyla...

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Detalles Bibliográficos
Autores principales: Appanah, Ruth, Dickerson, David R, Goyal, Preeti, Groudine, Mark, Lorincz, Matthew C
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2007
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1797817/
https://www.ncbi.nlm.nih.gov/pubmed/17305432
http://dx.doi.org/10.1371/journal.pgen.0030027

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1797817/
https://www.ncbi.nlm.nih.gov/pubmed/17305432
http://dx.doi.org/10.1371/journal.pgen.0030027

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