Synonymous Substitution Rates Predict HIV Disease Progression as a Result of Underlying Replication Dynamics

Upon HIV transmission, some patients develop AIDS in only a few months, while others remain disease free for 20 or more years. This variation in the rate of disease progression is poorly understood and has been attributed to host genetics, host immune responses, co-infection, viral genetics, and ada...

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Detalles Bibliográficos
Autores principales: Lemey, Philippe, Kosakovsky Pond, Sergei L, Drummond, Alexei J, Pybus, Oliver G, Shapiro, Beth, Barroso, Helena, Taveira, Nuno, Rambaut, Andrew
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2007
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1797821/
https://www.ncbi.nlm.nih.gov/pubmed/17305421
http://dx.doi.org/10.1371/journal.pcbi.0030029

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1797821/
https://www.ncbi.nlm.nih.gov/pubmed/17305421
http://dx.doi.org/10.1371/journal.pcbi.0030029

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