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New Insight into Intrachromosomal Deletions Induced by Chrysotile in the gpt delta Transgenic Mutation Assay

BACKGROUND: Genotoxicity is often a prerequisite to the development of malignancy. Considerable evidence has shown that exposure to asbestos fibers results in the generation of chromosomal aberrations and multilocus mutations using various in vitro approaches. However, there is less evidence to demo...

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Detalles Bibliográficos
Autores principales: Xu, An, Smilenov, Lubomir B., He, Peng, Masumura, Ken-ichi, Nohmi, Takehiko, Yu, Zengliang, Hei, Tom K.
Formato: Texto
Lenguaje:English
Publicado: National Institute of Environmental Health Sciences 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1797839/
https://www.ncbi.nlm.nih.gov/pubmed/17366825
http://dx.doi.org/10.1289/ehp.9425