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Screening for Developmental Neurotoxicity Using PC12 Cells: Comparisons of Organophosphates with a Carbamate, an Organochlorine, and Divalent Nickel

BACKGROUND: In light of the large number of chemicals that are potential developmental neurotoxicants, there is a need to develop rapid screening techniques. OBJECTIVES: We exposed undifferentiated and differentiating neuronotypic PC12 cells to different organophosphates (chlorpyrifos, diazinon, par...

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Detalles Bibliográficos
Autores principales: Slotkin, Theodore A., MacKillop, Emiko A., Ryde, Ian T., Tate, Charlotte A., Seidler, Frederic J.
Formato: Texto
Lenguaje:English
Publicado: National Institute of Environmental Health Sciences 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1797840/
https://www.ncbi.nlm.nih.gov/pubmed/17366826
http://dx.doi.org/10.1289/ehp.9527