Distal hinge of plasminogen activator inhibitor-1 involves its latency transition and specificities toward serine proteases

BACKGROUND: The plasminogen activator inhibitor-1 (PAI-1) spontaneously converts from an inhibitory into a latent form. Specificity of PAI-1 is mainly determined by its reactive site (Arg346-Met347), which interacts with serine residue of tissue-type plasminogen activator (tPA) with concomitant form...

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Detalles Bibliográficos
Autores principales: Wang, Qingcai, Shaltiel, Shmuel
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2003
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC179894/
https://www.ncbi.nlm.nih.gov/pubmed/12848892
http://dx.doi.org/10.1186/1471-2091-4-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC179894/
https://www.ncbi.nlm.nih.gov/pubmed/12848892
http://dx.doi.org/10.1186/1471-2091-4-5

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