Caspase-dependent proteolytic cleavage of STAT3α in ES cells, in mammary glands undergoing forced involution and in breast cancer cell lines

BACKGROUND: The STAT (Signal Transducers and Activators of Transcription) transcription factor family mediates cellular responses to a wide range of cytokines. Activated STATs (particularly STAT3) are found in a range of cancers. Further, STAT3 has anti-apoptotic functions in a range of tumour cell...

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Detalles Bibliográficos
Autores principales: Matthews, James R, Watson, Susan MR, Tevendale, Maxine CL, Watson, Christine J, Clarke, Alan R
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1800902/
https://www.ncbi.nlm.nih.gov/pubmed/17295906
http://dx.doi.org/10.1186/1471-2407-7-29

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1800902/
https://www.ncbi.nlm.nih.gov/pubmed/17295906
http://dx.doi.org/10.1186/1471-2407-7-29

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