Identifying allosteric fluctuation transitions between different protein conformational states as applied to Cyclin Dependent Kinase 2

BACKGROUND: The mechanisms underlying protein function and associated conformational change are dominated by a series of local entropy fluctuations affecting the global structure yet are mediated by only a few key residues. Transitional Dynamic Analysis (TDA) is a new method to detect these changes...

Descripción completa

Detalles Bibliográficos
Autores principales: Gu, Jenny, Bourne, Philip E
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1800904/
https://www.ncbi.nlm.nih.gov/pubmed/17286863
http://dx.doi.org/10.1186/1471-2105-8-45

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1800904/
https://www.ncbi.nlm.nih.gov/pubmed/17286863
http://dx.doi.org/10.1186/1471-2105-8-45

Ejemplares similares