Ligand Bound β1 Integrins Inhibit Procaspase-8 for Mediating Cell Adhesion-Mediated Drug and Radiation Resistance in Human Leukemia Cells

BACKGROUND: Chemo- and radiotherapeutic responses of leukemia cells are modified by integrin-mediated adhesion to extracellular matrix. To further characterize the molecular mechanisms by which β1 integrins confer radiation and chemoresistance, HL60 human acute promyelocytic leukemia cells stably tr...

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Detalles Bibliográficos
Autores principales: Estrugo, Doris, Fischer, Alexander, Hess, Franziska, Scherthan, Harry, Belka, Claus, Cordes, Nils
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2007
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1800908/
https://www.ncbi.nlm.nih.gov/pubmed/17342203
http://dx.doi.org/10.1371/journal.pone.0000269

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1800908/
https://www.ncbi.nlm.nih.gov/pubmed/17342203
http://dx.doi.org/10.1371/journal.pone.0000269

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