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Selective Alpha-Particle Mediated Depletion of Tumor Vasculature with Vascular Normalization

BACKGROUND: Abnormal regulation of angiogenesis in tumors results in the formation of vessels that are necessary for tumor growth, but compromised in structure and function. Abnormal tumor vasculature impairs oxygen and drug delivery and results in radiotherapy and chemotherapy resistance, respectiv...

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Detalles Bibliográficos
Autores principales: Jaggi, Jaspreet Singh, Henke, Erik, Seshan, Surya V., Kappel, Barry J., Chattopadhyay, Debjit, May, Chad, McDevitt, Michael R., Nolan, Daniel, Mittal, Vivek, Benezra, Robert, Scheinberg, David A.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1801076/
https://www.ncbi.nlm.nih.gov/pubmed/17342201
http://dx.doi.org/10.1371/journal.pone.0000267