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Selective Alpha-Particle Mediated Depletion of Tumor Vasculature with Vascular Normalization
BACKGROUND: Abnormal regulation of angiogenesis in tumors results in the formation of vessels that are necessary for tumor growth, but compromised in structure and function. Abnormal tumor vasculature impairs oxygen and drug delivery and results in radiotherapy and chemotherapy resistance, respectiv...
Autores principales: | , , , , , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2007
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1801076/ https://www.ncbi.nlm.nih.gov/pubmed/17342201 http://dx.doi.org/10.1371/journal.pone.0000267 |