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CT60 genotype does not affect CTLA-4 isoform expression despite association to T1D and AITD in northern Sweden

BACKGROUND: Polymorphisms in and around the CTLA-4 gene have previously been associated to T1D and AITD in several populations. One such single nucleotide polymorphism (SNP), CT60, has been reported to affect the expression level ratio of the soluble (sCTLA-4) to full length CTLA-4 (flCTLA-4) isofor...

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Detalles Bibliográficos
Autores principales: Mayans, Sofia, Lackovic, Kurt, Nyholm, Caroline, Lindgren, Petter, Ruikka, Karin, Eliasson, Mats, Cilio, Corrado M, Holmberg, Dan
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1802068/
https://www.ncbi.nlm.nih.gov/pubmed/17280620
http://dx.doi.org/10.1186/1471-2350-8-3