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Fragile X related protein 1 isoforms differentially modulate the affinity of fragile X mental retardation protein for G-quartet RNA structure

Fragile X syndrome, the most frequent form of inherited mental retardation, is due to the absence of expression of the Fragile X Mental Retardation Protein (FMRP), an RNA binding protein with high specificity for G-quartet RNA structure. FMRP is involved in several steps of mRNA metabolism: nucleocy...

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Detalles Bibliográficos
Autores principales: Bechara, Elias, Davidovic, Laetitia, Melko, Mireille, Bensaid, Mounia, Tremblay, Sandra, Grosgeorge, Josiane, Khandjian, Edouard W., Lalli, Enzo, Bardoni, Barbara
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2007
Materias:
RNA
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1802556/
https://www.ncbi.nlm.nih.gov/pubmed/17170008
http://dx.doi.org/10.1093/nar/gkl1021