Global analysis of microRNA target gene expression reveals that miRNA targets are lower expressed in mature mouse and Drosophila tissues than in the embryos

MicroRNAs (miRNAs) are non-coding small RNAs of ∼22 nt that regulate the gene expression by base pairing with target mRNAs, leading to mRNA cleavage or translational repression. It is currently estimated that miRNAs account for ∼1% of predicted genes in higher eukaryotic genomes and that up to 30% o...

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Detalles Bibliográficos
Autores principales: Yu, Zhenbao, Jian, Zhaofeng, Shen, Shi-Hsiang, Purisima, Enrico, Wang, Edwin
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2007
Materias:
Computational Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1802562/
https://www.ncbi.nlm.nih.gov/pubmed/17158157
http://dx.doi.org/10.1093/nar/gkl1032

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1802562/
https://www.ncbi.nlm.nih.gov/pubmed/17158157
http://dx.doi.org/10.1093/nar/gkl1032

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