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The p16(INK4a) tumor suppressor controls p21(WAF1) induction in response to ultraviolet light

p16(INK4a) and p21(WAF1), two major cyclin-dependent kinase inhibitors, are the products of two tumor suppressor genes that play important roles in various cellular metabolic pathways. p21(WAF1) is up-regulated in response to different DNA damaging agents. While the activation of p21(WAF1) is p53-de...

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Detalles Bibliográficos
Autores principales:	Al-Mohanna, Mai A., Al-Khalaf, Huda H., Al-Yousef, Nujoud, Aboussekhra, Abdelilah
Formato:	Texto
Lenguaje:	English
Publicado:	Oxford University Press 2007
Materias:	Molecular Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1802571/ https://www.ncbi.nlm.nih.gov/pubmed/17158160 http://dx.doi.org/10.1093/nar/gkl1075

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