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Development of a species-specific RNA polymerase I-based shRNA expression vector

RNA interference (RNAi) can be induced in vitro either by application of synthetic short interfering RNAs (siRNAs), or by intracellular expression of siRNAs or short hairpin RNAs (shRNAs) from transfected vectors. The most widely used promoters for siRNA/shRNA expression are based on polymerase III...

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Detalles Bibliográficos
Autores principales: Verca, M. S. Brenz, Weber, Peter, Mayer, Christine, Graf, Cornelia, Refojo, Damián, Kühn, Ralf, Grummt, Ingrid, Lutz, Beat
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1802596/
https://www.ncbi.nlm.nih.gov/pubmed/17158154
http://dx.doi.org/10.1093/nar/gkl1045